Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication

Lubov Salijanovna Kuchkarova; Gulchehkra Tengelbaevna Kudeshova

doi:doi:10.11648/j.ajbls.20160405.11

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Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication

Lubov Salijanovna Kuchkarova, Gulchehkra Tengelbaevna Kudeshova

Published in American Journal of Biomedical and Life Sciences (Volume 4, Issue 5)

Received: 13 August 2016 Accepted: 23 August 2016 Published: 9 September 2016

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Abstract

This study was conducted to know the effect of pectin on the α-amylase activity in the pancreas, intestine content and blood in growing rats with lead intoxication. After a single oral administration of lead acetate (80 mg/kg) to growing rats pectin was administered (400 mg/kg/12h) for 4 days. It is revealed that the administration of lead acetate causes an increase in pancreas weight, protein content in the pancreas and α-amylase activity in the pancreas and blood and reduced activity of the enzyme in the intestinal cavity in rats. Regular oral administration of pectin has a normalizing effect on pancreatic weight, protein content and on the level of the activity α-amylase in the pancreas, intestinal contents and blood in the 48-72 hours of observation in rats. These results support our suggestion about the possibility of the use of pectin for correcting of pancreatitis similar shifts at lead intoxication.

Published in	American Journal of Biomedical and Life Sciences (Volume 4, Issue 5)
DOI	10.11648/j.ajbls.20160405.11
Page(s)	69-74
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Rat, Lead Acetate, Pectin, α-Amylase, Pancreas

References

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Lubov Salijanovna Kuchkarova, Gulchehkra Tengelbaevna Kudeshova. (2016). Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication. American Journal of Biomedical and Life Sciences, 4(5), 69-74. https://doi.org/10.11648/j.ajbls.20160405.11

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ACS Style

Lubov Salijanovna Kuchkarova; Gulchehkra Tengelbaevna Kudeshova. Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication. Am. J. Biomed. Life Sci. 2016, 4(5), 69-74. doi: 10.11648/j.ajbls.20160405.11

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AMA Style

Lubov Salijanovna Kuchkarova, Gulchehkra Tengelbaevna Kudeshova. Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication. Am J Biomed Life Sci. 2016;4(5):69-74. doi: 10.11648/j.ajbls.20160405.11

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@article{10.11648/j.ajbls.20160405.11,
  author = {Lubov Salijanovna Kuchkarova and Gulchehkra Tengelbaevna Kudeshova},
  title = {Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {4},
  number = {5},
  pages = {69-74},
  doi = {10.11648/j.ajbls.20160405.11},
  url = {https://doi.org/10.11648/j.ajbls.20160405.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20160405.11},
  abstract = {This study was conducted to know the effect of pectin on the α-amylase activity in the pancreas, intestine content and blood in growing rats with lead intoxication. After a single oral administration of lead acetate (80 mg/kg) to growing rats pectin was administered (400 mg/kg/12h) for 4 days. It is revealed that the administration of lead acetate causes an increase in pancreas weight, protein content in the pancreas and α-amylase activity in the pancreas and blood and reduced activity of the enzyme in the intestinal cavity in rats. Regular oral administration of pectin has a normalizing effect on pancreatic weight, protein content and on the level of the activity α-amylase in the pancreas, intestinal contents and blood in the 48-72 hours of observation in rats. These results support our suggestion about the possibility of the use of pectin for correcting of pancreatitis similar shifts at lead intoxication.},
 year = {2016}
}

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TY  - JOUR
T1  - Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication
AU  - Lubov Salijanovna Kuchkarova
AU  - Gulchehkra Tengelbaevna Kudeshova
Y1  - 2016/09/09
PY  - 2016
N1  - https://doi.org/10.11648/j.ajbls.20160405.11
DO  - 10.11648/j.ajbls.20160405.11
T2  - American Journal of Biomedical and Life Sciences
JF  - American Journal of Biomedical and Life Sciences
JO  - American Journal of Biomedical and Life Sciences
SP  - 69
EP  - 74
PB  - Science Publishing Group
SN  - 2330-880X
UR  - https://doi.org/10.11648/j.ajbls.20160405.11
AB  - This study was conducted to know the effect of pectin on the α-amylase activity in the pancreas, intestine content and blood in growing rats with lead intoxication. After a single oral administration of lead acetate (80 mg/kg) to growing rats pectin was administered (400 mg/kg/12h) for 4 days. It is revealed that the administration of lead acetate causes an increase in pancreas weight, protein content in the pancreas and α-amylase activity in the pancreas and blood and reduced activity of the enzyme in the intestinal cavity in rats. Regular oral administration of pectin has a normalizing effect on pancreatic weight, protein content and on the level of the activity α-amylase in the pancreas, intestinal contents and blood in the 48-72 hours of observation in rats. These results support our suggestion about the possibility of the use of pectin for correcting of pancreatitis similar shifts at lead intoxication.
VL  - 4
IS  - 5
ER  -

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Author Information

Lubov Salijanovna Kuchkarova

Department of Physiology and Neurobiology, National University of Uzbekistan, Tashkent, Uzbekistan
Gulchehkra Tengelbaevna Kudeshova

Department of Physiology and Neurobiology, National University of Uzbekistan, Tashkent, Uzbekistan

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Lubov Salijanovna Kuchkarova, Gulchehkra Tengelbaevna Kudeshova. (2016). Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication. American Journal of Biomedical and Life Sciences, 4(5), 69-74. https://doi.org/10.11648/j.ajbls.20160405.11

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ACS Style

Lubov Salijanovna Kuchkarova; Gulchehkra Tengelbaevna Kudeshova. Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication. Am. J. Biomed. Life Sci. 2016, 4(5), 69-74. doi: 10.11648/j.ajbls.20160405.11

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AMA Style

Lubov Salijanovna Kuchkarova, Gulchehkra Tengelbaevna Kudeshova. Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication. Am J Biomed Life Sci. 2016;4(5):69-74. doi: 10.11648/j.ajbls.20160405.11

Copy | Download

@article{10.11648/j.ajbls.20160405.11,
  author = {Lubov Salijanovna Kuchkarova and Gulchehkra Tengelbaevna Kudeshova},
  title = {Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {4},
  number = {5},
  pages = {69-74},
  doi = {10.11648/j.ajbls.20160405.11},
  url = {https://doi.org/10.11648/j.ajbls.20160405.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20160405.11},
  abstract = {This study was conducted to know the effect of pectin on the α-amylase activity in the pancreas, intestine content and blood in growing rats with lead intoxication. After a single oral administration of lead acetate (80 mg/kg) to growing rats pectin was administered (400 mg/kg/12h) for 4 days. It is revealed that the administration of lead acetate causes an increase in pancreas weight, protein content in the pancreas and α-amylase activity in the pancreas and blood and reduced activity of the enzyme in the intestinal cavity in rats. Regular oral administration of pectin has a normalizing effect on pancreatic weight, protein content and on the level of the activity α-amylase in the pancreas, intestinal contents and blood in the 48-72 hours of observation in rats. These results support our suggestion about the possibility of the use of pectin for correcting of pancreatitis similar shifts at lead intoxication.},
 year = {2016}
}

Copy | Download

TY  - JOUR
T1  - Effect of Pectin on the Activity of Pancreatic α-Amylase in Growing Rats with Lead Intoxication
AU  - Lubov Salijanovna Kuchkarova
AU  - Gulchehkra Tengelbaevna Kudeshova
Y1  - 2016/09/09
PY  - 2016
N1  - https://doi.org/10.11648/j.ajbls.20160405.11
DO  - 10.11648/j.ajbls.20160405.11
T2  - American Journal of Biomedical and Life Sciences
JF  - American Journal of Biomedical and Life Sciences
JO  - American Journal of Biomedical and Life Sciences
SP  - 69
EP  - 74
PB  - Science Publishing Group
SN  - 2330-880X
UR  - https://doi.org/10.11648/j.ajbls.20160405.11
AB  - This study was conducted to know the effect of pectin on the α-amylase activity in the pancreas, intestine content and blood in growing rats with lead intoxication. After a single oral administration of lead acetate (80 mg/kg) to growing rats pectin was administered (400 mg/kg/12h) for 4 days. It is revealed that the administration of lead acetate causes an increase in pancreas weight, protein content in the pancreas and α-amylase activity in the pancreas and blood and reduced activity of the enzyme in the intestinal cavity in rats. Regular oral administration of pectin has a normalizing effect on pancreatic weight, protein content and on the level of the activity α-amylase in the pancreas, intestinal contents and blood in the 48-72 hours of observation in rats. These results support our suggestion about the possibility of the use of pectin for correcting of pancreatitis similar shifts at lead intoxication.
VL  - 4
IS  - 5
ER  -

Copy | Download