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Dementia Syndrome Revealing Acute Lymphoblastic Leukemia in Department of Neurology at Fann National Teaching Hospital in Dakar (Senegal)

Received: 19 January 2017     Accepted: 24 February 2017     Published: 27 March 2017
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Abstract

Dementia is a serious disease due to its morbidity and mortality. The etiology is dominated by Alzheimer's disease. However, there are dementia syndromes related to treatable and potentially curable cause. It’s rarely reported in clinical practice in our context. We report a case of dementia associated with lymphoblastic acute leukemia complicated by lymphocytic meningitis. F. ND aged 66, widow, unschooled and unemployed was hospitalized for gait disturbance and progressive appearance of memory disorders. On physical examination, there was a dementia syndrome, bilateral pyramidal syndrome. The rest of the clinical examination associated with additional tests (thoraco-abdominal-pelvic CT scan, lumbar puncture, and myelogram) was in favor of lymphocytic meningitis and acute lymphocytic leukemia. Dementia is a disease in which the search for the cause is crucial for considering an etiological support. Blood diseases such as LAL are treatable causes. The clinic provides a guidance element of research. Also, multidisciplinary care is necessary in these kinds of patients for a better development. This scientific cooperation must be done with, hematologists, internal medicine specialists and other colleagues.

Published in American Journal of Psychiatry and Neuroscience (Volume 5, Issue 2)
DOI 10.11648/j.ajpn.20170502.11
Page(s) 16-18
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Dementia, Acute Lymphoblastic Leukemia, Lymphocytic Meningitis, Senegal

References
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[2] François Sellal, Henri Becker. Démences potentiellement curables. Presse Med. 2007; 36: 289-98.
[3] Colin O, Julian A, Puyade M, Bouyer S, Meurin E, Blondeau S et al. Récidive neuroméningée d’une leucémie aiguë promyélocytaire révélée par un syndrome démentiel isolé. La Revue de Médecine Interne 2016.
[4] Ferlay J, Autier P, Boniol M, Heanue M, Colombet M, Boyle P. Estimates of the cancer incidence and mortality in Europe in 2006. Ann Oncol 2007; 18: 581-92.
[5] Brenner H. Long-term survival rates of cancer patients achieved by the end of the 20th century: a period analysis. Lancet 2002; 360: 1131-5.
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[8] Legriel S, Azoulay E. Complications neurologiques du patient d’oncohématologie Life threatening neurologic complications in patients with malignancies. Réanimation 2008; 17; 681-94.
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[10] Tattevin P, Revest M, Lavoué S. Méningites et méningoencéphalites aseptiques. Réanimation 2008; 17: 639: 50.
[11] Boumahni B, Lam Kam Sang L, Edmar A, Djemili S, Garnier C, Bangui A. Leucémie lymphoblastique aiguë révélée par une méningite lymphocytaire. Archives de Pédiatrie 2000; 7 (9): 1012–1013.
[12] Soumaré M, Seydi M, Ndour C. T, Fall N, Dieng Y, Sow A. I et al. Profil épidémiologique, clinique et étiologique des affections cérébroméningées observées à la clinique des maladies infectieuses du CHU de Fann à Dakar. Médecine et maladies infectieuses 35 (2005) 383–389.
[13] Yabroff KR, Lamont EB, Mariotto A, et al. Cost of care for elderly cancer patients in the United States. J Natl Cancer Inst 2008; 100: 630-41.
[14] Weytingh MD, Bossuyt PM, van Crevel H. Reversible dementia: more than 10%or less than 1%? A quantitative review. J Neurol 1995; 242: 466–71.
[15] O Colin, A Julian, M Puyade et al. Récidive neuroméningée d’une leucémie aiguë promyélocytairerévélée par un syndrome démentiel isolé. http://dx.doi.org/10.1016/j.revmed.2016.02.015.
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  • APA Style

    Ousmane Cisse, Marieme Soda Diop-Sène, Soumaila Boubacar, El Hadji Makhtar Ba, Fatoumata Ba, et al. (2017). Dementia Syndrome Revealing Acute Lymphoblastic Leukemia in Department of Neurology at Fann National Teaching Hospital in Dakar (Senegal). American Journal of Psychiatry and Neuroscience, 5(2), 16-18. https://doi.org/10.11648/j.ajpn.20170502.11

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    ACS Style

    Ousmane Cisse; Marieme Soda Diop-Sène; Soumaila Boubacar; El Hadji Makhtar Ba; Fatoumata Ba, et al. Dementia Syndrome Revealing Acute Lymphoblastic Leukemia in Department of Neurology at Fann National Teaching Hospital in Dakar (Senegal). Am. J. Psychiatry Neurosci. 2017, 5(2), 16-18. doi: 10.11648/j.ajpn.20170502.11

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    AMA Style

    Ousmane Cisse, Marieme Soda Diop-Sène, Soumaila Boubacar, El Hadji Makhtar Ba, Fatoumata Ba, et al. Dementia Syndrome Revealing Acute Lymphoblastic Leukemia in Department of Neurology at Fann National Teaching Hospital in Dakar (Senegal). Am J Psychiatry Neurosci. 2017;5(2):16-18. doi: 10.11648/j.ajpn.20170502.11

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  • @article{10.11648/j.ajpn.20170502.11,
      author = {Ousmane Cisse and Marieme Soda Diop-Sène and Soumaila Boubacar and El Hadji Makhtar Ba and Fatoumata Ba and Ibrahima Mariam Diallo and Ngor Side Diagne and Patrice Ntenga and Lala Bouna Seck and Kamador Touré and Moustapha Ndiaye and Amadou Gallo Diop and Mouhamadou Mansour Ndiaye},
      title = {Dementia Syndrome Revealing Acute Lymphoblastic Leukemia in Department of Neurology at Fann National Teaching Hospital in Dakar (Senegal)},
      journal = {American Journal of Psychiatry and Neuroscience},
      volume = {5},
      number = {2},
      pages = {16-18},
      doi = {10.11648/j.ajpn.20170502.11},
      url = {https://doi.org/10.11648/j.ajpn.20170502.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajpn.20170502.11},
      abstract = {Dementia is a serious disease due to its morbidity and mortality. The etiology is dominated by Alzheimer's disease. However, there are dementia syndromes related to treatable and potentially curable cause. It’s rarely reported in clinical practice in our context. We report a case of dementia associated with lymphoblastic acute leukemia complicated by lymphocytic meningitis. F. ND aged 66, widow, unschooled and unemployed was hospitalized for gait disturbance and progressive appearance of memory disorders. On physical examination, there was a dementia syndrome, bilateral pyramidal syndrome. The rest of the clinical examination associated with additional tests (thoraco-abdominal-pelvic CT scan, lumbar puncture, and myelogram) was in favor of lymphocytic meningitis and acute lymphocytic leukemia. Dementia is a disease in which the search for the cause is crucial for considering an etiological support. Blood diseases such as LAL are treatable causes. The clinic provides a guidance element of research. Also, multidisciplinary care is necessary in these kinds of patients for a better development. This scientific cooperation must be done with, hematologists, internal medicine specialists and other colleagues.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Dementia Syndrome Revealing Acute Lymphoblastic Leukemia in Department of Neurology at Fann National Teaching Hospital in Dakar (Senegal)
    AU  - Ousmane Cisse
    AU  - Marieme Soda Diop-Sène
    AU  - Soumaila Boubacar
    AU  - El Hadji Makhtar Ba
    AU  - Fatoumata Ba
    AU  - Ibrahima Mariam Diallo
    AU  - Ngor Side Diagne
    AU  - Patrice Ntenga
    AU  - Lala Bouna Seck
    AU  - Kamador Touré
    AU  - Moustapha Ndiaye
    AU  - Amadou Gallo Diop
    AU  - Mouhamadou Mansour Ndiaye
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    PY  - 2017
    N1  - https://doi.org/10.11648/j.ajpn.20170502.11
    DO  - 10.11648/j.ajpn.20170502.11
    T2  - American Journal of Psychiatry and Neuroscience
    JF  - American Journal of Psychiatry and Neuroscience
    JO  - American Journal of Psychiatry and Neuroscience
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    PB  - Science Publishing Group
    SN  - 2330-426X
    UR  - https://doi.org/10.11648/j.ajpn.20170502.11
    AB  - Dementia is a serious disease due to its morbidity and mortality. The etiology is dominated by Alzheimer's disease. However, there are dementia syndromes related to treatable and potentially curable cause. It’s rarely reported in clinical practice in our context. We report a case of dementia associated with lymphoblastic acute leukemia complicated by lymphocytic meningitis. F. ND aged 66, widow, unschooled and unemployed was hospitalized for gait disturbance and progressive appearance of memory disorders. On physical examination, there was a dementia syndrome, bilateral pyramidal syndrome. The rest of the clinical examination associated with additional tests (thoraco-abdominal-pelvic CT scan, lumbar puncture, and myelogram) was in favor of lymphocytic meningitis and acute lymphocytic leukemia. Dementia is a disease in which the search for the cause is crucial for considering an etiological support. Blood diseases such as LAL are treatable causes. The clinic provides a guidance element of research. Also, multidisciplinary care is necessary in these kinds of patients for a better development. This scientific cooperation must be done with, hematologists, internal medicine specialists and other colleagues.
    VL  - 5
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Author Information
  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Psychiatry, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

  • Department of Neurology, Fann National Teaching Hospital, Dakar, Senegal

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