Evaluation of Distribution Features of Bone Metastases by Bone Scintigraphy in Prostate Cancer

Ashraf Anas Zytoon; Eman Abdel Razek Tawfek; Adel Mohamed Elwakil; Gilan Ibrahim Aladle

doi:doi:10.11648/j.ijmi.20150306.15

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Evaluation of Distribution Features of Bone Metastases by Bone Scintigraphy in Prostate Cancer

Ashraf Anas Zytoon, Eman Abdel Razek Tawfek, Adel Mohamed Elwakil, Gilan Ibrahim Aladle

Published in International Journal of Medical Imaging (Volume 3, Issue 6)

Received: 31 October 2015 Accepted: 10 November 2015 Published: 26 November 2015

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Abstract

Prostate cancer (PCa) represents the most common non-cutaneous malignancy for men, where an estimated 241,740 new cases will be diagnosed in 2013 in the United States [1]. Whereas most of those new diagnoses will be clinically localized, up to 17% of patients may experience metastatic disease, in which the risk of cancer- specific mortality is increased [2]. In this context, it is well established that, beyond regional lymph nodes, the skeleton represents the most common metastatic site [3].The study aims to evaluate the pattern of distribution of bone metastases in prostate cancer patients by 99mTc- methylene diphosphonate (99mTc-MDP) bone scintigraphy. It was formed in 150 patients with pathologically proven prostate cancer and presented for bone scans with 99mTc-methylene diphosphonate (99mTc-MDP) for detection and evaluation of bone metastases. It was noted that patients with bone metastases had significantly higher frequency of bone pain when compared with patients without and noted that spine was the most commonly affected site (60.0 %) followed by ribs (52.0 %) and femur (30.0 %). Spread of bony metastases among the bony skeleton has distribution manner not only to the right or to the left. Metastatic bony lesions of prostate cancer are located mainly in spine (58.0%) followed by ribs (52.0 %) and femur (30.0 %). Patients with extensive bone metastasis had significantly higher frequency of skull, spine, scapula, humerous, sternum, ribs, iliac bone, ischium, and femur metastases

Published in	International Journal of Medical Imaging (Volume 3, Issue 6)
DOI	10.11648/j.ijmi.20150306.15
Page(s)	137-142
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Prostate Cancer, Bone Scan, Bone Metastases, MDP

References

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[4]	Russel P.J, P.Jackson,E.A. Kingsley. Prostate cancer methods and protocols. Methods in Molecular Medicine.2003; 81: 1-19.
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[17]	Scher B, Seitz M, Albinger W, et al. Value of PET and PET/CT in the diagnostics of prostate and penile cancer. Recent Results Cancer Res. 2008; 170: 159-79.
[18]	Levren G, Sadik M, Gjertsson P, et al. Relation between pain and skeletal metastasis in patients with prostate or breast cancer. Clin Physiol Funct Imaging. 2011 May; 31(3): 193-5.
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[20]	Elabbady A, Eid A, Fahmy A, et al. Pattern of prostate cancer presentation among the Egyptian population: A study in a single tertiary care center. Cent European J Urol. 2014; 67(4): 351-6.
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APA Style

Ashraf Anas Zytoon, Eman Abdel Razek Tawfek, Adel Mohamed Elwakil, Gilan Ibrahim Aladle. (2015). Evaluation of Distribution Features of Bone Metastases by Bone Scintigraphy in Prostate Cancer. International Journal of Medical Imaging, 3(6), 137-142. https://doi.org/10.11648/j.ijmi.20150306.15

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ACS Style

Ashraf Anas Zytoon; Eman Abdel Razek Tawfek; Adel Mohamed Elwakil; Gilan Ibrahim Aladle. Evaluation of Distribution Features of Bone Metastases by Bone Scintigraphy in Prostate Cancer. Int. J. Med. Imaging 2015, 3(6), 137-142. doi: 10.11648/j.ijmi.20150306.15

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AMA Style

Ashraf Anas Zytoon, Eman Abdel Razek Tawfek, Adel Mohamed Elwakil, Gilan Ibrahim Aladle. Evaluation of Distribution Features of Bone Metastases by Bone Scintigraphy in Prostate Cancer. Int J Med Imaging. 2015;3(6):137-142. doi: 10.11648/j.ijmi.20150306.15

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@article{10.11648/j.ijmi.20150306.15,
  author = {Ashraf Anas Zytoon and Eman Abdel Razek Tawfek and Adel Mohamed Elwakil and Gilan Ibrahim Aladle},
  title = {Evaluation of Distribution Features of Bone Metastases by Bone Scintigraphy in Prostate Cancer},
  journal = {International Journal of Medical Imaging},
  volume = {3},
  number = {6},
  pages = {137-142},
  doi = {10.11648/j.ijmi.20150306.15},
  url = {https://doi.org/10.11648/j.ijmi.20150306.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20150306.15},
  abstract = {Prostate cancer (PCa) represents the most common non-cutaneous malignancy for men, where an estimated 241,740 new cases will be diagnosed in 2013 in the United States [1]. Whereas most of those new diagnoses will be clinically localized, up to 17% of patients may experience metastatic disease, in which the risk of cancer- specific mortality is increased [2]. In this context, it is well established that, beyond regional lymph nodes, the skeleton represents the most common metastatic site [3].The study aims to evaluate the pattern of distribution of bone metastases in prostate cancer patients by 99mTc- methylene diphosphonate (99mTc-MDP) bone scintigraphy. It was formed in 150 patients with pathologically proven prostate cancer and presented for bone scans with 99mTc-methylene diphosphonate (99mTc-MDP) for detection and evaluation of bone metastases. It was noted that patients with bone metastases had significantly higher frequency of bone pain when compared with patients without and noted that spine was the most commonly affected site (60.0 %) followed by ribs (52.0 %) and femur (30.0 %). Spread of bony metastases among the bony skeleton has distribution manner not only to the right or to the left. Metastatic bony lesions of prostate cancer are located mainly in spine (58.0%) followed by ribs (52.0 %) and femur (30.0 %). Patients with extensive bone metastasis had significantly higher frequency of skull, spine, scapula, humerous, sternum, ribs, iliac bone, ischium, and femur metastases},
 year = {2015}
}

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TY  - JOUR
T1  - Evaluation of Distribution Features of Bone Metastases by Bone Scintigraphy in Prostate Cancer
AU  - Ashraf Anas Zytoon
AU  - Eman Abdel Razek Tawfek
AU  - Adel Mohamed Elwakil
AU  - Gilan Ibrahim Aladle
Y1  - 2015/11/26
PY  - 2015
N1  - https://doi.org/10.11648/j.ijmi.20150306.15
DO  - 10.11648/j.ijmi.20150306.15
T2  - International Journal of Medical Imaging
JF  - International Journal of Medical Imaging
JO  - International Journal of Medical Imaging
SP  - 137
EP  - 142
PB  - Science Publishing Group
SN  - 2330-832X
UR  - https://doi.org/10.11648/j.ijmi.20150306.15
AB  - Prostate cancer (PCa) represents the most common non-cutaneous malignancy for men, where an estimated 241,740 new cases will be diagnosed in 2013 in the United States [1]. Whereas most of those new diagnoses will be clinically localized, up to 17% of patients may experience metastatic disease, in which the risk of cancer- specific mortality is increased [2]. In this context, it is well established that, beyond regional lymph nodes, the skeleton represents the most common metastatic site [3].The study aims to evaluate the pattern of distribution of bone metastases in prostate cancer patients by 99mTc- methylene diphosphonate (99mTc-MDP) bone scintigraphy. It was formed in 150 patients with pathologically proven prostate cancer and presented for bone scans with 99mTc-methylene diphosphonate (99mTc-MDP) for detection and evaluation of bone metastases. It was noted that patients with bone metastases had significantly higher frequency of bone pain when compared with patients without and noted that spine was the most commonly affected site (60.0 %) followed by ribs (52.0 %) and femur (30.0 %). Spread of bony metastases among the bony skeleton has distribution manner not only to the right or to the left. Metastatic bony lesions of prostate cancer are located mainly in spine (58.0%) followed by ribs (52.0 %) and femur (30.0 %). Patients with extensive bone metastasis had significantly higher frequency of skull, spine, scapula, humerous, sternum, ribs, iliac bone, ischium, and femur metastases
VL  - 3
IS  - 6
ER  -

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Author Information

Ashraf Anas Zytoon

Radiology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt
Eman Abdel Razek Tawfek

Nuclear Medicine & Clinical Oncology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt
Adel Mohamed Elwakil

Radiology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt
Gilan Ibrahim Aladle

Radiology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt

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APA Style

Ashraf Anas Zytoon, Eman Abdel Razek Tawfek, Adel Mohamed Elwakil, Gilan Ibrahim Aladle. (2015). Evaluation of Distribution Features of Bone Metastases by Bone Scintigraphy in Prostate Cancer. International Journal of Medical Imaging, 3(6), 137-142. https://doi.org/10.11648/j.ijmi.20150306.15

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ACS Style

Ashraf Anas Zytoon; Eman Abdel Razek Tawfek; Adel Mohamed Elwakil; Gilan Ibrahim Aladle. Evaluation of Distribution Features of Bone Metastases by Bone Scintigraphy in Prostate Cancer. Int. J. Med. Imaging 2015, 3(6), 137-142. doi: 10.11648/j.ijmi.20150306.15

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AMA Style

Ashraf Anas Zytoon, Eman Abdel Razek Tawfek, Adel Mohamed Elwakil, Gilan Ibrahim Aladle. Evaluation of Distribution Features of Bone Metastases by Bone Scintigraphy in Prostate Cancer. Int J Med Imaging. 2015;3(6):137-142. doi: 10.11648/j.ijmi.20150306.15

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@article{10.11648/j.ijmi.20150306.15,
  author = {Ashraf Anas Zytoon and Eman Abdel Razek Tawfek and Adel Mohamed Elwakil and Gilan Ibrahim Aladle},
  title = {Evaluation of Distribution Features of Bone Metastases by Bone Scintigraphy in Prostate Cancer},
  journal = {International Journal of Medical Imaging},
  volume = {3},
  number = {6},
  pages = {137-142},
  doi = {10.11648/j.ijmi.20150306.15},
  url = {https://doi.org/10.11648/j.ijmi.20150306.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20150306.15},
  abstract = {Prostate cancer (PCa) represents the most common non-cutaneous malignancy for men, where an estimated 241,740 new cases will be diagnosed in 2013 in the United States [1]. Whereas most of those new diagnoses will be clinically localized, up to 17% of patients may experience metastatic disease, in which the risk of cancer- specific mortality is increased [2]. In this context, it is well established that, beyond regional lymph nodes, the skeleton represents the most common metastatic site [3].The study aims to evaluate the pattern of distribution of bone metastases in prostate cancer patients by 99mTc- methylene diphosphonate (99mTc-MDP) bone scintigraphy. It was formed in 150 patients with pathologically proven prostate cancer and presented for bone scans with 99mTc-methylene diphosphonate (99mTc-MDP) for detection and evaluation of bone metastases. It was noted that patients with bone metastases had significantly higher frequency of bone pain when compared with patients without and noted that spine was the most commonly affected site (60.0 %) followed by ribs (52.0 %) and femur (30.0 %). Spread of bony metastases among the bony skeleton has distribution manner not only to the right or to the left. Metastatic bony lesions of prostate cancer are located mainly in spine (58.0%) followed by ribs (52.0 %) and femur (30.0 %). Patients with extensive bone metastasis had significantly higher frequency of skull, spine, scapula, humerous, sternum, ribs, iliac bone, ischium, and femur metastases},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - Evaluation of Distribution Features of Bone Metastases by Bone Scintigraphy in Prostate Cancer
AU  - Ashraf Anas Zytoon
AU  - Eman Abdel Razek Tawfek
AU  - Adel Mohamed Elwakil
AU  - Gilan Ibrahim Aladle
Y1  - 2015/11/26
PY  - 2015
N1  - https://doi.org/10.11648/j.ijmi.20150306.15
DO  - 10.11648/j.ijmi.20150306.15
T2  - International Journal of Medical Imaging
JF  - International Journal of Medical Imaging
JO  - International Journal of Medical Imaging
SP  - 137
EP  - 142
PB  - Science Publishing Group
SN  - 2330-832X
UR  - https://doi.org/10.11648/j.ijmi.20150306.15
AB  - Prostate cancer (PCa) represents the most common non-cutaneous malignancy for men, where an estimated 241,740 new cases will be diagnosed in 2013 in the United States [1]. Whereas most of those new diagnoses will be clinically localized, up to 17% of patients may experience metastatic disease, in which the risk of cancer- specific mortality is increased [2]. In this context, it is well established that, beyond regional lymph nodes, the skeleton represents the most common metastatic site [3].The study aims to evaluate the pattern of distribution of bone metastases in prostate cancer patients by 99mTc- methylene diphosphonate (99mTc-MDP) bone scintigraphy. It was formed in 150 patients with pathologically proven prostate cancer and presented for bone scans with 99mTc-methylene diphosphonate (99mTc-MDP) for detection and evaluation of bone metastases. It was noted that patients with bone metastases had significantly higher frequency of bone pain when compared with patients without and noted that spine was the most commonly affected site (60.0 %) followed by ribs (52.0 %) and femur (30.0 %). Spread of bony metastases among the bony skeleton has distribution manner not only to the right or to the left. Metastatic bony lesions of prostate cancer are located mainly in spine (58.0%) followed by ribs (52.0 %) and femur (30.0 %). Patients with extensive bone metastasis had significantly higher frequency of skull, spine, scapula, humerous, sternum, ribs, iliac bone, ischium, and femur metastases
VL  - 3
IS  - 6
ER  -

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